Can You Get Botox While On Antibiotics?

Antibiotics target bacteria, while Botox is a protein, immune to their action, but can you safely mix them? Can You Get Botox While On Antibiotics? A question that pops up often, leaving many feeling a bit confused. Some individuals worry antibiotics might “break down” Botox, reducing its effectiveness. Thankfully, this isn’t the case!


This is a brand name for botulinum toxin A, a protein that weakens muscles by temporarily blocking nerve signals. It’s used for various medical and cosmetic purposes, such as treating wrinkles, muscle spasms, and chronic migraines.

Can You Get Botox While Taking Antibiotics?

Certain antibiotics can have neuromuscular blocking effects. This means they can weaken muscles, similar to how Botox works. Combining them could increase the risk of muscle weakness. While most antibiotics won’t directly interfere with Botox®, a few exceptions exist. The key lies in understanding the types of antibiotics and their potential interactions.


Aminoglycosides are a class of powerful antibiotics used to treat serious bacterial infections, particularly those caused by gram-negative bacteria. They work by interfering with the bacteria’s ability to make proteins, essentially stopping them from growing and multiplying.

These antibiotics can have muscle-relaxing effects, potentially amplifying Botox muscle relaxation and increasing the risk of side effects like weakness. Some common types of Aminoglycosides  are:

  • Gentamicin
  • Neomycin
  • Tobramycin
  • Amikacin


Fluoroquinolones are a class of broad-spectrum antibiotics used to treat a wide range of bacterial infections. There have been rare reports of muscle weakness or respiratory distress in patients taking fluoroquinolone antibiotics and receiving botox injections, particularly for myasthenia gravis (a neuromuscular disease). Some common Fluoroquinolones include:

  • Ciprofloxacin (Cipro)
  • Levofloxacin (Levaquin)
  • Ofloxacin (Floxin)
  • Norfloxacin (Noroxin)
  • Moxifloxacin (Avelox)

Amoxicillin Is Not Considered To Contraindicate Botox:

Studies and clinical experience have not shown any significant problems with taking amoxicillin alongside Botox. Amoxicillin targets bacteria, while Botox works on the nervous system, so their mechanisms of action do not interfere with each other. It’s one of the most commonly prescribed antibiotics that doesn’t interact with toxins in any significant way.

Interaction Between Botox And Antibiotics:

The interaction between both depends on various factors such as:

  • Specific antibiotic
  • Individual Patient Health
  • Dosage and Duration
  • Purpose of treatment

How Long To Wait Between Completing A Course Of Antibiotics And Botox Treatment?

A minimum of 7 days is recommended after finishing the antibiotic course before receiving Botox. This allows enough time for the antibiotics to clear from your system and minimizes the risk of any potential interaction.

Our qualified experts will determine the optimal wait time based on your specific situation. They’ll consider the above-mentioned factors and set the timeline to ensure your safety and the effectiveness of both the antibiotics and the Botox treatment. Contact AIVI Aesthetics today, and let’s work together and review your medical history and any potential interactions to determine if Botox is right for you while on antibiotics.

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Specials May 2024