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What Age Should You Start Rejuran Treatments?
If you’ve ever Googled what age should you start Rejuran — you’re not alone. At AIVI Aesthetics in Agoura Hills, we often recommend starting in your late 20s to mid-40s, depending on your skin concerns.
Let’s break it down.
What Is Rejuran?
Rejuran Healer is a regenerative injectable treatment made from polynucleotides (PN) derived from salmon DNA. It works by healing damaged skin, stimulating collagen production, and improving texture, hydration, and elasticity.
It’s a powerful skin booster that works at a cellular level — perfect for those who want to look refreshed without adding volume like fillers.
Ideal Age to Start Rejuran
Late 20s to Early 30s: Preventative Care
This is the best time to start banking collagen before visible aging starts. If you’re noticing dullness, early fine lines, or post-acne pigmentation, Rejuran can repair the skin barrier and improve tone.
Mid-30s to 40s: Skin Correction & Repair
This is the age when signs of aging like texture irregularities, fine lines, enlarged pores, and loss of bounce become more noticeable. Rejuran can help restore skin elasticity, boost hydration, and reduce inflammation and redness.
40s and Beyond: Skin Recovery & Anti-Aging
Even in your 40s, 50s, and beyond, Rejuran can still provide remarkable improvement. It’s ideal for sensitive, thinning, or aging skin, and can be paired with RF microneedling or laser to maximize results.
Why Start Sooner Rather Than Later?
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Boost collagen before it’s lost.
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Prevent early signs of aging.
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Recover from acne scarring or sun damage.
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Improve skin texture and glow naturally.
Rejuran isn’t just for anti-aging — it’s for anyone who wants to improve skin health from within.
Studies on polynucleotides and collagen stimulation suggest early intervention supports better long-term results by preventing skin damage and boosting natural healing.
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You might also want to read: The Secret to Smooth, Youthful Skin in Agoura Hills
How Often Should You Get Rejuran?
For best results:
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Initial series: 3-4 sessions spaced 2–4 weeks apart
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Maintenance: 1 session every 3–6 months
Who Should Consider Rejuran?
You may be a good candidate if you:
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Have sensitive or inflamed skin
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See early signs of aging
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Want skin healing without adding volume
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Struggle with acne scars or pigmentation
Personalized Plans at AIVI Aesthetics
Whether you’re 28 or 48, we tailor your treatment based on skin condition, goals, and age. Rejuran can be part of a comprehensive rejuvenation plan, especially when combined with RF microneedling, vitamin-infused facials, or exosomes.
Check our exclusive offers here!
Final Thoughts
There’s no perfect age to start Rejuran — it depends on your skin’s needs. But the earlier you begin, the more proactive you are in preserving your youthful, healthy glow. Think of it as investing in long-term skin vitality.
Ready to begin? Book your Rejuran consultation at AIVI Aesthetics today or call/text us at (818) 851-9900.
References:
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Park, K. Y., et al. (2015). “Clinical effects of salmon DNA-based product on skin rejuvenation.” Journal of Cosmetic and Laser Therapy, 17(2), 99–104.
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Kim, H. J., et al. (2010). “PDRN, a mixture of deoxyribonucleotides, activates human fibroblasts.” Annals of Dermatology, 22(2), 143–148.
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You might want to read Rejuran Healer for Acne & Acne Scars



